Kinetic proofreading in receptor-mediated transduction of cellular signals: receptor aggregation, partially activated receptors, and cytosolic messengers

DOI10.1006/BULM.2002.0306MaRDI QIDQ253289zbMATH OpenOpenAlexWikidataFDO

Authors William S. Hlavacek, Carla Wofsy, Byron Goldstein, Antonio Naranjo Redondo

Publication date 8 March 2016

Published in Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1006/bulm.2002.0306

zbMATH Keywords

cytosolic messengersimmunoreceptor Fc\(\epsilon\)RIkinetic proofreadingT cell receptor

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

Recommendations

• T cell sensitivity and specificity-kinetic proofreading revisited
• T cell activation: Kinetic proofreading, serial engagement and cell adhesion
• Elucidation of T cell signalling models
• Stochastic effects and bistability in T cell receptor signaling
• Receptor-dependent sensitivity of NF-\(\kappa\)B to low physiological level

Cited in

(9)

• A logical analysis of the process of T cell activation: different consequences depending on the state of CD28 engagement
• Analysis of Fn14-NF-\(\kappa\)B signaling response dynamics using a mechanistic model
• Stochastic effects and bistability in T cell receptor signaling
• T cell activation: Kinetic proofreading, serial engagement and cell adhesion
• T cell sensitivity and specificity-kinetic proofreading revisited
• Nonequilibrium sensing and its analogy to kinetic proofreading
• Rare event simulation for T-cell activation
• Quantifying the strength of ligand antagonism in TCR triggering
• Modeling and analysis of early events in T-lymphocyte antigen-activated intracellular-signalling pathways

This page was built for publication: Kinetic proofreading in receptor-mediated transduction of cellular signals: receptor aggregation, partially activated receptors, and cytosolic messengers

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q253289)