Mitochondrial mutations and ageing: can mitochondrial deletion mutants accumulate via a size based replication advantage?

DOI10.1016/J.JTBI.2013.09.009MaRDI QIDQ2632352zbMATHOpenAlexWikidataFDO

Authors Axel Kowald, Marcus Dawson, Thomas B. L. Kirkwood

Publication date 14 May 2019

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2013.09.009

zbMATH Keywords

mathematical modelageingmitochondrial mutation

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Genetics and epigenetics (92D10)

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Cited in

(2)

• Stochastic models for evolving cellular populations of mitochondria: disease, development, and ageing
• A comparison of mtDNA deletion mutant proliferation mechanisms

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