Mitochondrial mutations and ageing: can mitochondrial deletion mutants accumulate via a size based replication advantage?

DOI10.1016/J.JTBI.2013.09.009zbMATH Open1411.92197OpenAlexW2057945098WikidataQ47209396 ScholiaQ47209396MaRDI QIDQ2632352FDOQ2632352

Authors: Axel Kowald, Marcus Dawson, Thomas B. L. Kirkwood 

Publication date: 14 May 2019

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2013.09.009

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zbMATH Keywords

mathematical modelageingmitochondrial mutation

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Genetics and epigenetics (92D10)

Cited In (2)

• A comparison of mtDNA deletion mutant proliferation mechanisms
• Stochastic models for evolving cellular populations of mitochondria: disease, development, and ageing

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