Study of the behaviour of proliferating cells in leukemia modelled by a system of delay differential equations

zbMATH Open1349.37018arXiv1403.2966MaRDI QIDQ2806695FDOQ2806695

Authors: Anca-Veronica Ion 

Publication date: 18 May 2016

Published in: Analele Științifice ale Universității ``Ovidius Constanța. Seria: Matematică (Search for Journal in Brave)

Abstract: For the model of periodic chronic myelogenous leukemia considered by Pujo-Menjouet, Mackey et al., model consisting of two delay differential equations, the equation for the density of so-called "resting cells" was studied from numerical and qualitative point of view in several works. In this paper we focus on the equation for the density of proliferating cells and study it from a qualitative point of view.

Full work available at URL: https://arxiv.org/abs/1403.2966

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zbMATH Keywords

stabilityHopf bifurcationdelay differential equationsqualitative analysisBautin bifurcationleukemia model

Mathematics Subject Classification ID

Dynamical systems in biology (37N25) Stability theory for smooth dynamical systems (37C75) Bifurcations of limit cycles and periodic orbits in dynamical systems (37G15) Normal forms for dynamical systems (37G05) Numerical methods for functional-differential equations (65L03)

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