Optimal individualized dosing strategies: a pharmacologic approach to developing dynamic treatment regimens for continuous-valued treatments

DOI10.1002/BIMJ.201400244MaRDI QIDQ2806836zbMATHOpenAlexWikidataFDO

Authors Benjamin Rich, David A. Stephens, Erica E. M. Moodie

Publication date 19 May 2016

Published in Biometrical Journal (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1002/bimj.201400244

zbMATH Keywords

G-estimationdynamic treatment regimensadaptive individualized dosinganticoagulation therapycontinuous dosesdesign of sequential trials

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Medical applications (general) (92C50)

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Cites work

• A note on the variance of doubly-robust G-estimators
• Demystifying Optimal Dynamic Treatment Regimes
• Dose-response relationship from longitudinal data with response-dependent dose modification using likelihood methods
• Estimating optimal dynamic regimes correcting bias under the null
• G-estimation and artificial censoring: problems, challenges, and applications
• Identifying the consequences of dynamic treatment strategies: a decision-theoretic overview
• Optimal Dynamic Treatment Regimes
• Proceedings of the second Seattle symposium in biostatistics. Analysis of correlated data, Seattle, WA, USA, November 20--21, 2000.
• Regret-Regression for Optimal Dynamic Treatment Regimes
• Statistical methods for dynamic treatment regimes. Reinforcement learning, causal inference, and personalized medicine

Cited in

(9)

• Adaptive protocols based on predictions from a mechanistic model of the effect of IL7 on CD4 counts
• A new approach towards minimizing the risk of misdosing warfarin initiation doses
• Privacy-preserving estimation of an optimal individualized treatment rule: a case study in maximizing time to severe depression-related outcomes
• Pharmacokinetically guided optimum adaptive dose selection in early phase clinical trials
• scientific article; zbMATH DE number 7599168 (Why is no real title available?)
• Optimal drug dosage subject to constraints
• Doubly robust estimation of optimal dosing strategies
• scientific article; zbMATH DE number 5257966 (Why is no real title available?)
• Preserving data privacy when using multi-site data to estimate individualized treatment rules

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