Basic Principles in Modeling Adaptive Regulation and Immunodominance

DOI10.1007/978-1-4614-4178-6_2zbMath1345.92092OpenAlexW96948925MaRDI QIDQ2820373

Peter P. Lee, Peter S. Kim, Doron Levy

Publication date: 16 September 2016

Published in: Lecture Notes on Mathematical Modelling in the Life Sciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/978-1-4614-4178-6_2

zbMATH Keywords

apoptosisepitopesdormancyimmunodominance

Mathematics Subject Classification ID

Physiology (general) (92C30) Medical epidemiology (92C60)

Related Items (4)

Modeling LSD1-mediated tumor stagnation ⋮ Modeling the development of cellular exhaustion and tumor-immune stalemate ⋮ Robustness of dengue complex network under targeted versus random attack ⋮ Two-mode network modeling and analysis of dengue epidemic behavior in Gombak, Malaysia

Cites Work

• A theory of immunodominance and adaptive regulation
• Epitope down-modulation as a mechanism for the coexistence of competing T-cells
• Emergent group dynamics governed by regulatory cells produce a robust primary T cell response
• Models of CD8+ responses: 1. what is the antigen-independent proliferation program
• How regulatory CD25+CD4+T cells impinge on tumor immunobiology? On the existence of two alternative dynamical classes of tumors

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