Efficient design for clinically relevant intent-to-treat comparisons

zbMATH Open1397.92321MaRDI QIDQ2829293FDOQ2829293

Ree Dawson, Philip W. Lavori

Publication date: 27 October 2016

Recommendations

• Sequential multiple assignment randomization trials with enrichment design
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• Comparison of designs for adaptive treatment strategies: Baseline vs. adaptive randomization
• Imputing missing data from sequential multiple assignment randomized trials

zbMATH Keywords

dynamic treatment regimesequential multiple assignment randomized trialintention to treat principle

Mathematics Subject Classification ID

Medical applications (general) (92C50) Statistical block designs (62K10) General biostatistics (92B15)

Cited In (2)

• Optimizing randomized trial designs to distinguish which subpopulations benefit from treatment
• Efficient design and inference for multistage randomized trials of individualized treatment policies

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