Comparisons of allocating sample size rationally into individual regions under heterogeneous effect size in a multiregional trial by a fixed effect model and a random effect model

DOI10.1080/03610926.2014.974823zbMath1349.62548OpenAlexW2514560364MaRDI QIDQ2834658

Feng-shou Ko

Publication date: 23 November 2016

Published in: Communications in Statistics - Theory and Methods (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1080/03610926.2014.974823

zbMATH Keywords

clinical trialexperience designsimlilarity

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Related Items (3)

Discussion on the issue of sample size determination for a targeted to an untargeted and to a mixed effect model-based clinical trial design ⋮ An alternate approach for sample size determination in a multi-regional trial ⋮ Comparisons of a multi-regional trial for four or five regions by fixed effect model and random effect model about allocating sample size rationally into individual regions for a multi-regional trial

Cites Work

• A Design For Survival Studies: A Multi-regional Trial With Unrecognized Heterogeneity
• Approaches to Allocate Sample Size Rationally Into Individual Regions for a Multi-regional Trial Under Heterogeneous Effect Size

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