Collapsing SNP genotypes in case-control genome-wide association studies increases the type I error rate and power

DOI10.2202/1544-6115.1325zbMATH Open1276.92068OpenAlexW2053317073WikidataQ37461414 ScholiaQ37461414MaRDI QIDQ2863986FDOQ2863986

Authors: Abigail G. Matthews, Chad Haynes, Chang Liu, Jurg Ott 

Publication date: 5 December 2013

Published in: Statistical Applications in Genetics and Molecular Biology (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc2789285

Recommendations

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zbMATH Keywords

type I error rategenome-wide association

Mathematics Subject Classification ID

Genetics and epigenetics (92D10)

Cited In (2)

• Leveraging local identity-by-descent increases the power of case/control GWAS with related individuals
• Increase of rejection rate in case-control studies with the differential genotyping error rates

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