Breast cancer diagnosis from proteomic mass spectrometry data: a comparative evaluation

DOI10.2202/1544-6115.1435MaRDI QIDQ2864029zbMATHOpenAlexWikidataFDO

Authors David J. Hand

Publication date 5 December 2013

Published in Statistical Applications in Genetics and Molecular Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.2202/1544-6115.1435

zbMATH Keywords

sensitivityclassificationspecificityerror rateclassifier performanceproteomic mass spectra

Mathematics Subject Classification ID

Medical applications (general) (92C50)

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• Case-control breast cancer study of MALDI-TOF proteomic mass spectrometry data on serum samples
• Gradient boosting for high-dimensional prediction of rare events
• Classification of breast cancer versus normal samples from mass spectrometry profiles using linear discriminant analysis of important features selected by random forest
• Breast cancer prediction using the isotonic separation technique
• On the use of double cross-validation for the combination of proteomic mass spectral data for enhanced diagnosis and prediction
• Detection of cancer-specific markers amid massive mass spectral data
• International Competition on Mass Spectrometry Proteomic Diagnosis
• Organizing a competition on clinical mass spectrometry based proteomic diagnosis
• Finding causative genes from high-dimensional data: an appraisal of statistical and machine learning approaches
• A classification model for the Leiden proteomics competition
• Developing a discrimination rule between breast cancer patients and controls using proteomics mass spectrometric data: a three-step approach
• Prototype based fuzzy classification in clinical proteomics

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