Weighted multiple hypothesis testing procedures

DOI10.2202/1544-6115.1437MaRDI QIDQ2864072zbMATH OpenOpenAlexWikidataFDO

Authors Guolian Kang, Keying Ye, Nianjun Liu, David B. Allison, Guimin Gao

Publication date 5 December 2013

Published in Statistical Applications in Genetics and Molecular Biology (Search for Journal in Brave)

Full work available at URL https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703613

zbMATH Keywords

family-wise error ratemultiple hypothesis testingweightBonferroni procedureŠidák procedure

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Genetics and epigenetics (92D10) Paired and multiple comparisons; multiple testing (62J15)

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(8)

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• Multiple comparisons in genetic association studies: a hierarchical modeling approach
• Different weights of tests within a start‐up demonstration procedure
• Classes of multiple decision functions strongly controlling FWER and FDR
• Covariate Powered Cross-Weighted Multiple Testing
• Power-enhanced multiple decision functions controlling family-wise error and false discovery rates
• A powerful truncated tail strength method for testing multiple null hypotheses in one dataset
• Optimally weighted, fixed sequence and gatekeeper multiple testing procedures

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