Simplification of reversible Markov chains by removal of states with low equilibrium occupancy

DOI10.1016/J.JTBI.2012.07.007MaRDI QIDQ293758zbMATH OpenOpenAlexWikidataFDO

Authors Ghanim Ullah, William J. Bruno, John E. Pearson

Publication date 9 June 2016

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL http://hdl.handle.net/1808/24527

zbMATH Keywords

ligand-bindinglow-occupancy statesmodel simplificationMWC modelreversible Markov chains

Mathematics Subject Classification ID

Applications of Markov chains and discrete-time Markov processes on general state spaces (social mobility, learning theory, industrial processes, etc.) (60J20) General biology and biomathematics (92B05) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

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Cites work

• scientific article; zbMATH DE number 6791332 (Why is no real title available?)
• A new look at the statistical model identification
• Estimating the dimension of a model
• Markov Chains
• Phase transitions and metastability in Markovian and molecular systems
• Reciprocal Relations in Irreversible Processes. I.
• Robust algorithm for random resistor networks using hierarchical domain structure
• The Use of Wye-Delta Transformations in Network Simplification

Cited in

(2)

• Measuring edge importance: a quantitative analysis of the stochastic shielding approximation for random processes on graphs
• Simplification of irreversible Markov chains by removal of states with fast leaving rates

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