Allocating recycled significance levels in group sequential procedures for multiple endpoints

DOI10.1002/bimj.201300157zbMath1309.62019OpenAlexW1631629704WikidataQ51018490 ScholiaQ51018490MaRDI QIDQ2938309

Ajit C. Tamhane, Dong Xi

Publication date: 14 January 2015

Published in: Biometrical Journal (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1002/bimj.201300157

zbMATH Keywords

recyclingfamilywise error rategraphical approacherror spending functionO'Brien-Fleming boundaryPocock boundary

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical analysis (62L10) Graphical methods in statistics (62A09)

Related Items

Sample size optimization and initial allocation of the significance levels in group sequential trials with multiple endpoints ⋮ A unified framework for weighted parametric group sequential design

Uses Software

• mvtnorm

Cites Work

• Computation of multivariate normal and \(t\) probabilities
• Testing a Primary and a Secondary Endpoint in a Group Sequential Design
• Discrete Sequential Boundaries for Clinical Trials
• Closed Testing Procedures for Group Sequential Clinical Trials with Multiple Endpoints
• The Evaluation of General Non-Centred Orthant Probabilities
• On Adaptive Extensions of Group Sequential Trials for Clinical Investigations
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