Dynamics and stability of a three-dimensional model of cell signal transduction with delay

DOI10.1088/0951-7715/28/7/2515zbMATH Open1356.35265OpenAlexW2414864971MaRDI QIDQ2944174FDOQ2944174

Authors: Chris Levy, David Iron 

Publication date: 28 August 2015

Published in: Nonlinearity (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1088/0951-7715/28/7/2515

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zbMATH Keywords

signal transductiondelay differential equationsnumerical simulationsperturbation methodslocalized structures

Mathematics Subject Classification ID

Numerical methods for differential-algebraic equations (65L80) Stability in context of PDEs (35B35) Bifurcations in context of PDEs (35B32) Asymptotic expansions of solutions to PDEs (35C20) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Finite element, Rayleigh-Ritz and Galerkin methods for boundary value problems involving PDEs (65N30) Cell biology (92C37) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Perturbations, asymptotics of solutions to ordinary differential equations (34E10) Numerical analysis (educational aspects) (97N40)

Cited In (9)

• A Model of the Signal Transduction Process under a Delay
• Model of cell signal transduction in a three-dimensional domain
• Weakly nonlinear theory for oscillatory dynamics in a one-dimensional PDE-ODE model of membrane dynamics coupled by a bulk diffusion field
• An asymptotic analysis of a 2-D model of dynamically active compartments coupled by bulk diffusion
• Stability and dynamics of spike-type solutions to delayed Gierer-Meinhardt equations
• Delayed reaction kinetics and the stability of spikes in the Gierer-Meinhardt model
• Dynamics in three cells with multiple time delays
• A delay-differential equation model of the signal transduction pathway
• Dynamics and stability of a three-dimensional model of cell signal transduction

Uses Software

• Matlab
• COMSOL

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