Models and Optimal Control in Freezing and Thawing of Living Cells and Tissues

DOI10.1007/978-3-319-05083-6_10zbMATH Open1327.49009OpenAlexW263473274MaRDI QIDQ2945484FDOQ2945484

Nikolai D. Botkin, Varvara L. Turova, Karl-Heinz Hoffmann

Publication date: 11 September 2015

Published in: International Series of Numerical Mathematics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/978-3-319-05083-6_10

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zbMATH Keywords

Hamilton-Jacobi equationsmathematical modelcontrol systemgrid methodsdamaging factorsfreezing and thawing of biological cellsoptimal cooling and warming rates

Mathematics Subject Classification ID

Hamilton-Jacobi equations (35F21) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Existence theories for optimal control problems involving partial differential equations (49J20) Dynamic programming in optimal control and differential games (49L20) Finite difference methods for initial value and initial-boundary value problems involving PDEs (65M06) General biology and biomathematics (92B05)

Cited In (6)

• The front-tracking ALE method: application to a model of the freezing of cell suspensions
• Analytical optimal controls for the state constrained addition and removal of cryoprotective agents
• Entropy generation at the cellular level during freezing process of biological materials
• Simulation of micro-scale interaction between ice and biological cells.
• Optimal control in cryopreservation of cells and tissues
• Fundamentals of cryobiology. Physical phenomena and mathematical models

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