Inverse problems of combined photoacoustic and optical coherence tomography

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Publication:2960159

DOI10.1002/MMA.3915zbMATH Open1355.92058arXiv1601.03320OpenAlexW2235144595WikidataQ30365067 ScholiaQ30365067MaRDI QIDQ2960159FDOQ2960159


Authors: Peter Elbau, Leonidas Mindrinos, Otmar Scherzer Edit this on Wikidata


Publication date: 7 February 2017

Published in: Mathematical Methods in the Applied Sciences (Search for Journal in Brave)

Abstract: Optical coherence tomography (OCT) and photoacoustic tomography (PAT) are emerging non-invasive biological and medical imaging techniques. It is a recent trend in experimental science to design experiments that perform PAT and OCT imaging at once. In this paper we present a mathematical model describing the dual experiment. Since OCT is mathematically modelled by Maxwell's equations or some simplifications of it, whereas the light propagation in quantitative photoacoustics is modelled by (simplifications of) the radiative transfer equation, the first step in the derivation of a mathematical model of the dual experiment is to obtain a unified mathematical description, which in our case are Maxwell's equations. As a by-product we therefore derive a new mathematical model of photoacoustic tomography based on Maxwell's equations. It is well known by now, that without additional assumptions on the medium, it is not possible to uniquely reconstruct all optical parameters from either one of these modalities alone. We show that in the combined approach one has additional information, compared to a single modality, and the inverse problem of reconstruction of the optical parameters becomes feasible.


Full work available at URL: https://arxiv.org/abs/1601.03320




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