Estimating the probability of clonal relatedness of pairs of tumors in cancer patients

DOI10.1111/BIOM.12710zbMath1415.62121OpenAlexW2605551205WikidataQ38797971 ScholiaQ38797971MaRDI QIDQ3119844

Venkatraman E. Seshan, Colin B. Begg, Audrey Mauguen, Irina Ostrovnaya

Publication date: 13 March 2019

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: https://biostats.bepress.com/cgi/viewcontent.cgi?article=1034&context=mskccbiostat

zbMATH Keywords

random effectsconditional likelihoodmutational testingclonal relatednessdiagnostic probability

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Measures of association (correlation, canonical correlation, etc.) (62H20) Genetics and epigenetics (92D10)

Uses Software

• LBFGS-B

Cites Work

• Using somatic mutation data to test tumors for clonal relatedness
• A Limited Memory Algorithm for Bound Constrained Optimization
• Semiparametric Analysis of Zero‐Inflated Count Data
• Statistical Tests for Clonality

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