Assessing statistical significance in variance components linkage analysis: a theoretical justification

DOI10.1016/J.JSPI.2016.06.002MaRDI QIDQ313109zbMATHOpenAlexFDO

Authors Gengxin Li, Yuehua Cui

Publication date 9 September 2016

Published in Journal of Statistical Planning and Inference (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jspi.2016.06.002

zbMATH Keywords

likelihood ratio testidentity-by-decentlinkage analysismixture chi-squarequantitative trait loci

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Asymptotic properties of parametric tests (62F05) Hypothesis testing in multivariate analysis (62H15)

Recommendations

• Reconsidering the asymptotic null distribution of likelihood ratio tests for genetic linkage in multivariate variance components models under complete pleiotropy
• Calculating asymptotic significance levels of the constrained likelihood ratio test with application to multivariate genetic linkage analysis
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• Some results in genetic linkage analysis
• Likelihood ratio tests for genetic linkage

Cites work

• scientific article; zbMATH DE number 1220667 (Why is no real title available?)
• scientific article; zbMATH DE number 3323651 (Why is no real title available?)
• A GENERALIZED MULTIVARIATE ANALOGUE OF THE ONE SIDED TEST
• A REDUCTION FORMULA FOR NORMAL MULTIVARIATE INTEGRALS
• A multivariate analogue of the one-sided test
• Asymptotic Properties of Maximum Likelihood Estimators and Likelihood Ratio Tests Under Nonstandard Conditions
• Asymptotic distribution of test statistics in the analysis of moment structures under inequality constraints
• Calculating asymptotic significance levels of the constrained likelihood ratio test with application to multivariate genetic linkage analysis
• Genetic linkage methods for quantitative traits
• NOTE ON BIAS IN THE ESTIMATION OF AUTOCORRELATION
• On the Distribution of the Likelihood Ratio
• On the asymptotics of constrained \(M\)-estimation
• On the asymptotics of constrained local \(M\)-estimators.
• Towards a Unified Theory of Inequality Constrained Testing in Multivariate Analysis

Cited in

(2)

• Reconsidering the asymptotic null distribution of likelihood ratio tests for genetic linkage in multivariate variance components models under complete pleiotropy
• Calculating asymptotic significance levels of the constrained likelihood ratio test with application to multivariate genetic linkage analysis

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