Optimal feedback strategies for bacterial growth with degradation, recycling, and effect of temperature

DOI10.1002/OCA.2398MaRDI QIDQ3176489zbMATH OpenOpenAlexWikidataFDO

Authors Ivan Yegorov, Francis Mairet, Jean-Luc Gouzé

Publication date 20 July 2018

Published in Optimal Control Applications \& Methods (Search for Journal in Brave)

Full work available at URL https://archimer.ifremer.fr/doc/00434/54592/

zbMATH Keywords

optimal controlPontryagin's maximum principleresource allocationrecyclingbacterial growtheffect of temperatureprotein degradationfeedback strategyswitching curvesingular regimechattering regime

Mathematics Subject Classification ID

Physiological, cellular and medical topics (92C99) Optimality conditions for problems involving ordinary differential equations (49K15) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Feedback control (93B52)

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(12)

• Simultaneous versus sequential optimal experiment design for the identification of multi-parameter microbial growth kinetics as a function of temperature
• Optimal control of bacterial growth for the maximization of metabolite production
• Dynamical analysis and optimization of a generalized resource allocation model of microbial growth
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• Optimal choice between feedforward and feedback control in gene expression to cope with unpredictable danger
• Optimal strategies in the treatment of cancers in the Lotka-Volterra mathematical model of competition
• Probabilistic safety and optimal control for survival analysis of bacillus subtilis
• Optimal spiral-like solutions near a singular extremal in a two-input control problem
• Unifying temperature effects on the growth rate of bacteria and the stability of globular proteins
• Neighborhood of the second-order singular regime in problems with control in a disk
• Optimal bacterial resource allocation: metabolite production in continuous bioreactors
• The biokinetic spectrum for temperature and optimal Darwinian fitness

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