Significance Tests for Cancer Screening Trials

DOI10.2307/2531689zbMATH Open0715.62230OpenAlexW2331831802WikidataQ69745413 ScholiaQ69745413MaRDI QIDQ3201526FDOQ3201526

Authors: Robert E. Tarone, John J. Gart 

Publication date: 1989

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.2307/2531689

Recommendations

• Planning clinical trials to evaluate early detection programmes
• Estimating case-fatality reduction from randomized screening trials
• Optimal tests for carcinogenicity in a model with fatal and incidental tumours.
• Estimating Lead Time and Sensitivity in a Screening Program without Estimating the Incidence in the Screened Group
• Probability modeling and statistical inference in periodic cancer screening

zbMATH Keywords

score testsufficient statisticPoisson modelsasymptotic relative efficienciesuniformly most powerful unbiased testcancer screening trial

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cited In (6)

• Planning of randomized early detection trials
• A Novel Design for Estimating Relative Accuracy of Screening Tests When Complete Disease Verification Is Not Feasible
• Design and testing for clinical trials faced with misclassified causes of death
• The use of modeling to understand the impact of screening on US mortality: examples from mammography and PSA testing
• Estimating case-fatality reduction from randomized screening trials
• A holistic analysis of Poisson data with application to a trial of selenium and cancer deaths

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