Adjoint sensitivity analysis of a tumor growth model and its application to spatiotemporal radiotherapy optimization

DOI10.3934/MBE.2016034zbMATH Open1349.92073OpenAlexW2514873267WikidataQ50561905 ScholiaQ50561905MaRDI QIDQ326540FDOQ326540

Authors: Krzysztof Fujarewicz, Krzysztof Łakomiec 

Publication date: 12 October 2016

Published in: Mathematical Biosciences and Engineering (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.3934/mbe.2016034

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zbMATH Keywords

sensitivity analysisdifference equationspartial differential equationstumor growthspatial systems

Mathematics Subject Classification ID

Numerical optimization and variational techniques (65K10) Medical applications (general) (92C50) Finite difference methods for initial value and initial-boundary value problems involving PDEs (65M06)

Cites Work

• A mathematical model for brain tumor response to radiation therapy
• System Engineering Approach to Planning Anticancer Therapies
• Artificial Intelligence and Soft Computing - ICAISC 2004
• Parameter estimation of systems with delays via structural sensitivity analysis
• On fitting of mathematical models of cell signaling pathways using adjoint systems

Cited In (1)

• Estimation of initial functions for systems with delays from discrete measurements

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