A spatially distributed computational model of brain cellular metabolism

DOI10.1016/J.JTBI.2015.03.037MaRDI QIDQ327110zbMATH OpenOpenAlexWikidataFDO

Authors Daniela Calvetti, Yougan Cheng, Erkki Somersalo

Publication date 19 October 2016

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2015.03.037

zbMATH Keywords

reaction-diffusion equationKrogh cylindermulti-domain modelreduction of dimensionalitywell-mixed lumped model

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Neural biology (92C20) Computational methods for problems pertaining to biology (92-08) Cell biology (92C37)

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Cites work

• scientific article; zbMATH DE number 852532 (Why is no real title available?)
• Bayesian stationary state flux balance analysis for a skeletal muscle metabolic model
• Capillary supply regions
• Dynamic activation model for a glutamatergic neurovascular unit
• Simulating patterns of excitation, repolarization and action potential duration with cardiac bidomain and monodomain models
• Time scale of diffusion in molecular and cellular biology

Cited in

(9)

• A new approach to study in vivo cellular metabolism using a modellistic analysis of magnetic resonance spectra
• Improving the prediction of local drug distribution profiles in the brain with a new 2D mathematical model
• Brain energetics plays a key role in the coordination of electrophysiology, metabolism and hemodynamics: evidence from an integrated computational model
• Sampling-Based Analysis of a Spatially Distributed Model for Liver Metabolism at Steady State
• A computational model integrating brain electrophysiology and metabolism highlights the key role of extracellular potassium and oxygen
• A spatially distributed model of brain metabolism highlights the role of diffusion in brain energy metabolism
• Modeling brain energy metabolism and function: a multiparametric monitoring approach
• Uncertainty quantification in flux balance analysis of spatially lumped and distributed models of neuron-astrocyte metabolism
• A computational multiscale model of cortical spreading depression propagation

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