Global threshold dynamics of a stochastic differential equation SIS model

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Publication:342901

DOI10.1016/J.JMAA.2016.10.041zbMATH Open1350.92057arXiv1506.02342OpenAlexW2962806908WikidataQ115346014 ScholiaQ115346014MaRDI QIDQ342901FDOQ342901


Authors: Chuang Xu Edit this on Wikidata


Publication date: 18 November 2016

Published in: Journal of Mathematical Analysis and Applications (Search for Journal in Brave)

Abstract: In this paper, we further investigate the global dynamics of a stochastic differential equation SIS (Susceptible-Infected-Susceptible) epidemic model recently proposed in [A. Gray et al., SIAM. J. Appl. Math., 71 (2011), 876-902]. We present a stochastic threshold theorem in term of a extit{stochastic basic reproduction number} R0S: the disease dies out with probability one if R0S<1, and the disease is recurrent if R0Sgeqslant1. We prove the existence and global asymptotic stability of a unique invariant density for the Fokker-Planck equation associated with the SDE SIS model when R0S>1. In term of the profile of the invariant density, we define a extit{persistence basic reproduction number} R0P and give a persistence threshold theorem: the disease dies out with large probability if R0Pleqslant1, while persists with large probability if R0P>1. Comparing the extit{stochastic disease prevalence} with the extit{deterministic disease prevalence}, we discover that the stochastic prevalence is bigger than the deterministic prevalence if the deterministic basic reproduction number R0D>2. This shows that noise may increase severity of disease. Finally, we study the asymptotic dynamics of the stochastic SIS model as the noise vanishes and establish a sharp connection with the threshold dynamics of the deterministic SIS model in term of a extit{Limit Stochastic Threshold Theorem}.


Full work available at URL: https://arxiv.org/abs/1506.02342




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