Fixed and sequential treatment allocation in clinical trials

MaRDI QIDQ3497646zbMATH OpenFDO

Authors Afaf M. Mady

Publication date 27 July 2009

Full work available at URL http://pphmj.com/abstract/4038.htm

zbMATH Keywords

minimax approachBayesian approachmaximin approachsequential trial

Mathematics Subject Classification ID

Parametric hypothesis testing (62F03) Bayesian inference (62F15) Applications of statistics to biology and medical sciences; meta analysis (62P10) Medical applications (general) (92C50) Statistical ranking and selection procedures (62F07) Sequential statistical design (62L05) Bayesian problems; characterization of Bayes procedures (62C10) Minimax procedures in statistical decision theory (62C20)

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(9)

• Sample Size Determination in Clinical Trials with an Emphasis on Exponentially Distributed Responses
• Bounded deficiency in the comparison of the means of two normal populations
• A comparison of seven allocation rules for a clinical trial model
• Sequential allocation in clinical trials
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• A randomized two stage allocation for continuous response clinical trials
• Comparing exponential clinical trials by combining individual sequential experiments available from independent studies
• Effect of delayed observations on fixed design for exponential distribution
• Gittins indices and constrained allocation in clinical trials

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