Switching and diffusion models for gene regulation networks

DOI10.1137/080735412MaRDI QIDQ3549897zbMATH OpenOpenAlexFDO

Authors Somkid Intep, Desmond J. Higham, Xuerong Mao

Publication date 30 March 2010

Published in Multiscale Modeling & Simulation (Search for Journal in Brave)

Full work available at URL https://strathprints.strath.ac.uk/13621/

zbMATH Keywords

diffusionGillespie's algorithmhybrid modelItô lemmaMarkov chainslow scale simulationstochastic simulation algorithmtranscriptiontransition ratetranslation

Mathematics Subject Classification ID

Stochastic ordinary differential equations (aspects of stochastic analysis) (60H10) Applications of stochastic analysis (to PDEs, etc.) (60H30) Applications of statistics to biology and medical sciences; meta analysis (62P10) Numerical solutions to stochastic differential and integral equations (65C30) Systems biology, networks (92C42) Classical flows, reactions, etc. in chemistry (92E20)

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(12)

• A numerical characteristic method for probability generating functions on stochastic first-order reaction networks
• Zero, one and two-switch models of gene regulation
• System with switchings as models of regulatory modules in genomic cell systems
• Approximate analysis of biological systems by hybrid switching jump diffusion
• Convergence properties of posttranslationally modified protein-protein switching networks with fast decay rates
• scientific article; zbMATH DE number 2104186 (Why is no real title available?)
• Infection time in multistable gene networks. A backward stochastic variational inequality with nonconvex switch-dependent reflection approach
• A stochastic switch with different phases
• Bistable switching asymptotics for the self regulating gene
• Hybrid simulation of autoregulation within transcription and translation
• scientific article; zbMATH DE number 2232773 (Why is no real title available?)
• Continuous-switch piecewise quadratic models of biological networks: application to bacterial growth

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