Interactions between stably rolling leukocytes in vivo
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Publication:3554873
DOI10.1063/1.1829972zbMATH Open1187.76274arXivphysics/0310082OpenAlexW2001237298MaRDI QIDQ3554873FDOQ3554873
Authors: Michael R. King, Aimee D. Ruscio, Michael B. Kim, Ingrid H. Sarelius 
Publication date: 22 April 2010
Published in: Physics of Fluids (Search for Journal in Brave)
Abstract: We have characterized the two-dimensional spatial dependence of the hydrodynamic interactions between two adhesively rolling leukocytes in a live venule in the mouse cremaster muscle. Two rolling leukocytes were observed to slow each other down when rolling together in close proximity, due to mutual sheltering from the external blood flow in the vessel lumen. These results are in agreement with a previous study of leukocyte rolling interactions using carbohydrate-coated beads in a parallel-plate flow chamber and a detailed computer model of adhesion in a multicellular environment.
Full work available at URL: https://arxiv.org/abs/physics/0310082
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