Multi-phase Stefan problems for a non-linear one-dimensional model of cell-to-cell adhesion and diffusion

DOI10.1017/S0956792509990167MaRDI QIDQ3557539zbMATH OpenFDO

Authors Keith Anguige

Publication date 23 April 2010

Published in European Journal of Applied Mathematics (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/0902.4561

zbMATH Keywords

diffusionStefan problem

Mathematics Subject Classification ID

Stability in context of PDEs (35B35) PDEs in connection with classical thermodynamics and heat transfer (35Q79) Stefan problems, phase changes, etc. (80A22)

Abstract: We consider a family of multi-phase Stefan problems for a certain 1-d model of cell-to-cell adhesion and diffusion, which takes the form of a nonlinear forward-backward parabolic equation. In each material phase the cell density stays either high or low, and phases are connected by jumps across an `unstable' interval. We develop an existence theory for such problems which allows for the annihilation of phases and the subsequent continuation of solutions. Stability results for the long-time behaviour of solutions are also obtained, and, where necessary, the analysis is complemented by numerical simulations.

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Cites work

• A one-dimensional model of cell diffusion and aggregation, incorporating volume filling and cell-to-cell adhesion
• Dynamic theory of quasilinear parabolic systems. III: Global existence
• Dynamics and Coarsening of Interfaces for the Viscous Cahn—Hilliard Equation in One Spatial Dimension

Cited in

(6)

• Analysis and asymptotic reduction of a bulk-surface reaction-diffusion model of Gierer-Meinhardt type
• Continuum and lattice models analysis of the aggregation diffusion cell movement
• Finite traveling wave solutions in a degenerate cross-diffusion model for bacterial colony with volume filling
• Global existence for a bulk/surface model for active-transport-induced polarisation in biological cells
• A one-dimensional model for the interaction between cell-to-cell adhesion and chemotactic signalling
• On the approximation and efficient evaluation of integral terms in PDE models of cell adhesion

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