Models for prediction of anti-HIV-1 activity of 5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones using random forest, decision tree and moving average analysis

DOI10.3233/JCM-2009-0256MaRDI QIDQ3560657zbMATH OpenOpenAlexWikidataFDO

Authors Rohit Dutt, Harish Dureja, A. K. Madan

Publication date 14 May 2010

Published in Journal of Computational Methods in Sciences and Engineering (Search for Journal in Brave)

Full work available at URL https://doi.org/10.3233/jcm-2009-0256

zbMATH Keywords

molecular descriptorsanti- HIV-1 agentsdihydro-alkoxy-benzyl-oxopyrimidinesE-Dragon softwaretopochemical descriptors

Mathematics Subject Classification ID

Medical applications (general) (92C50) Biochemistry, molecular biology (92C40) Computational methods for problems pertaining to biology (92-08)

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(1)

• Predicting inhibition constants of antimalarial drug compounds using support vector regression

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