Optimal parametric design with applications to pharmacokinetic and pharmacodynamic trials

DOI10.1080/02664760600743571zbMath1119.62353OpenAlexW1984467288MaRDI QIDQ3592626

Jixian Wang

Publication date: 13 September 2007

Published in: Journal of Applied Statistics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1080/02664760600743571

zbMATH Keywords

pharmacokinetic modelsD-optimal designmodel discriminationparametric designPK/PD modelsrepeated measure design

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Optimal statistical designs (62K05)

Related Items (2)

Optimal Designs for Quantile Regression Models ⋮ Optimal designs for rational regression models

Cites Work

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• Optimal design with bounded density: Optimization algorithms of the exchange type
• Optimal Design via Curve Fitting of Monte Carlo Experiments
• Consequences and Detection of Misspecified Nonlinear Regression Models
• The design of experiments for discriminating between two rival models
• Optimum Experimental Designs for Properties of a Compartmental Model
• Optimal design in random-effects regression models
• A Limited Memory Algorithm for Bound Constrained Optimization
• The Sequential Generation of $D$-Optimum Experimental Designs

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