The analysis of multicentre clinical trials when there is heterogeneity between centres

DOI10.1080/00949650802168969zbMATH Open1183.62192OpenAlexW2049752783MaRDI QIDQ3653258FDOQ3653258

Authors: Markus Neuhäuser, Roswitha Senske 

Publication date: 22 December 2009

Published in: Journal of Statistical Computation and Simulation (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1080/00949650802168969

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zbMATH Keywords

non-parametric analysiscombination testmulticentre trialvan Elteren test

Mathematics Subject Classification ID

Nonparametric hypothesis testing (62G10) Applications of statistics to biology and medical sciences; meta analysis (62P10) Testing in survival analysis and censored data (62N03)

Cites Work

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• A stagewise rejective multiple test procedure based on a modified Bonferroni test
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• Combining Independent Tests of Significance
• A systematic comparison of methods for combining \(p\)-values from independent tests
• Weighted rank statistics in factorial designs with fixed effects
• A Consensus Combined P-Value Test and the Family-Wide Significance of Component Tests

Cited In (5)

• Rank-based analyses of stratified experiments: alternatives to the van Elteren test
• Analysis of homogeneity of treatment effect in adaptive multicenter clinical trials
• Randomization-based nonparametric methods for the analysis of multicentre trials
• Randomization-based nonparametric methods for the analysis of multicentre trials
• A modified combination test for the analysis of a clinical trial when a protocol amendment changed the inclusion criteria

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