Dose-response models for time-to-response toxicity data

DOI10.2307/3314709zbMath0519.62095OpenAlexW2000057313MaRDI QIDQ3668701

John van Ryzin, John D. Kalbfleisch, Daniel Krewski

Publication date: 1983

Published in: Canadian Journal of Statistics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.2307/3314709

zbMATH Keywords

hazard functioncompartmental modelscompeting riskslog-linear modelsrisk assessmentmaximum-likelihood estimationCox regression modelsurvival distributiondose-response modelscause-specific hazardsmultievent modelsmixed population modelsmultiple-decrement modelstime-to-response toxicity data

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Parametric inference (62F99)

Related Items (4)

Bootstrap bounds for “safe” doses in the multistage cancer dose-response model ⋮ A carcinogenesis model describing mutational events at the DNA adduct level ⋮ A survival model and estimation of time to tumor ⋮ Analytic expressions for maximum likelihood estimators in a nonparametric model of tumor incidence and death

Cites Work

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• Two-event models for carcinogenesis: Incidence curves for childhood and adult tumors
• Asymptotic theory for analyzing dose-response survival data with application to the low-dose extrapolation problem
• Estimating dependent life lengths, with applications to the theory of competing risks
• Compartmental analysis of carcinogenic experiments: Formulation of a stochastic model
• Maximum likelihood estimation of dose-response functions subject to absolutely monotonic constraints
• Tests for Differences in Tumor Incidence Based on Animal Carcinogenesis Experiments
• Carcinogenic Risk Assessment: A Guide to the Literature
• A Generalized Multihit Dose-Response Model for Low-Dose Extrapolation
• A nonidentifiability aspect of the problem of competing risks.
• Partial likelihood
• A Review and Critique of Some Models Used in Competing Risk Analysis
• Discrimination among some parametric models
• Age incidence curves for cancer.
• Confidence Intervals and Test of Hypotheses Concerning Dose Response Relations Inferred from Animal Carcinogenicity Data
• The Analysis of Failure Times in the Presence of Competing Risks
• On constant-sum models for censored survival data
• Stochastic Models of Compartmental Systems
• Testing Disease Dependence in Survival Experiments with Serial Sacrifice
• Nonparametric Estimation of Lifetime and Disease Onset Distributions from Incomplete Observations

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