Analysis of repeated measures designs with changing covariates in clinical trials

DOI10.1093/BIOMET/73.3.707MaRDI QIDQ3757228zbMATH OpenOpenAlexFDO

Authors H. I. Patel

Publication date 1986

Published in Biometrika (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1093/biomet/73.3.707

zbMATH Keywords

changing covariateclinical trialslikelihood ratio testslinear hypothesesmaximum likelihood estimatorsmultivariate modelmultivariate normalityrepeated measures designstwo-period crossover designwithin-subject covariates

Mathematics Subject Classification ID

Hypothesis testing in multivariate analysis (62H15) Design of statistical experiments (62K99) Applications of statistics to biology and medical sciences; meta analysis (62P10)

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Cited in

(14)

• Statistical model of changes in repeated multivariate measurements associated with the development of disease
• Application of seemingly unrelated regression in medical data with intermittently observed time-dependent covariates
• Analysis of cross-over designs via growth curve models
• A step-down procedure for analysis of time-varying covariates in multi-visit studies
• Analysis of repeated measures designs with changing covariates
• Scheffés mixed model for multivariate repeated measures:a relative efficiency evaluation
• Generalized multivariate models for longitudinal data
• The Cgmanova Model
• Equivalence of maximum likelihood estimation and iterative two-stage estimation for seemingly unrelated regression models
• Analysis of a within-subject design with covariates
• General multivariate linear models for longitudional studies
• A Variance Components Model for Analyzing Repeated Measures Designs with Non-Stationary Error Structure
• Multivariate regression models for discrete and continuous repeated measurements
• The new TSME method of covariance estimator for repeated measures crossover design

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