Analysis of repeated measures designs with changing covariates in clinical trials

DOI10.1093/BIOMET/73.3.707zbMATH Open0621.62104OpenAlexW1973278468MaRDI QIDQ3757228FDOQ3757228

Authors: H. I. Patel 

Publication date: 1986

Published in: Biometrika (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1093/biomet/73.3.707

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zbMATH Keywords

clinical trialsmultivariate normalitylikelihood ratio testsmaximum likelihood estimatorsmultivariate modellinear hypothesesrepeated measures designschanging covariatetwo-period crossover designwithin-subject covariates

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Hypothesis testing in multivariate analysis (62H15) Design of statistical experiments (62K99)

Cited In (12)

• A step-down procedure for analysis of time-varying covariates in multi-visit studies
• Multivariate regression models for discrete and continuous repeated measurements
• Analysis of cross-over designs via growth curve models
• Equivalence of maximum likelihood estimation and iterative two-stage estimation for seemingly unrelated regression models
• Application of seemingly unrelated regression in medical data with intermittently observed time-dependent covariates
• The new TSME method of covariance estimator for repeated measures crossover design
• The Cgmanova Model
• General multivariate linear models for longitudional studies
• Statistical model of changes in repeated multivariate measurements associated with the development of disease
• Scheffés mixed model for multivariate repeated measures:a relative efficiency evaluation
• Generalized multivariate models for longitudinal data
• Analysis of repeated measures designs with changing covariates

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