Extending the conditions of application of an inversion of the Hodgkin-Huxley gating model

DOI10.1007/S11538-013-9832-7zbMath1311.92049OpenAlexW2019880954WikidataQ37373438 ScholiaQ37373438MaRDI QIDQ376463

Charles Antzelevitch, Jonathan M. Cordeiro, Ashley E. Raba, Jacques Beaumont

Publication date: 5 November 2013

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s11538-013-9832-7

zbMATH Keywords

inverse problemnonlinear parameter estimationHodgkin-Huxley modelmembrane current kineticsvoltage clamp data analysis

Mathematics Subject Classification ID

Neural biology (92C20) Physiology (general) (92C30)

Related Items (3)

Estimability analysis and optimal design in dynamic multi-scale models of cardiac electrophysiology ⋮ Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage-clamp experiments ⋮ Dynamics of pivoting electrical waves in a cardiac tissue model

Uses Software

• VCell
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Cites Work

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• An improved parameter estimation method for Hodgkin-Huxley models
• On the interpretation of voltage-clamp data using the Hodgkin-Huxley model
• Estimation of the steady-state characteristics of the Hodgkin-Huxley model from voltage-clamp data
• Parameter Estimation of the Hodgkin--Huxley Gating Model: An Inversion Procedure

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