Spatial aspects in the SMAD signaling pathway

DOI10.1007/S00285-012-0574-1MaRDI QIDQ378304zbMATH OpenOpenAlexWikidataFDO

Authors E. Friedmann, R. Rannacher, T. Szekeres, Juliane Claus, Ursula Klingmüller

Publication date 11 November 2013

Published in Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/s00285-012-0574-1

zbMATH Keywords

finite elementscell signalingmesh generationmixed differential equations

Mathematics Subject Classification ID

Reaction-diffusion equations (35K57) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Computational methods for problems pertaining to biology (92-08) Cell biology (92C37)

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Cites work

• An asymptotic analysis of intracellular signaling gradients arising from multiple small compart\-ments

Cited in

(5)

• An asymptotic analysis of intracellular signaling gradients arising from multiple small compart\-ments
• A mathematical model of the stoichiometric control of Smad complex formation in TGF-\(\beta\) signal transduction pathway
• Intracellular protein dynamics as a mathematical problem
• Well-posedness of a linear spatio-temporal model of the JAK2/STAT5 signaling pathway
• Lyapunov analysis of the spatially discrete-continuous system dynamics

Describes a project that uses

Uses Software

• GASCOIGNE
• ANSYS

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