Investigation of disease-free survival as a surrogate endpoint for survival in cancer clinical trials

DOI10.1080/03610929808832163MaRDI QIDQ3842893zbMATH OpenOpenAlexFDO

Authors T. Timothy Chen, Edward L. Korn, Stewart J. Anderson, Anne S. Lindblad, Harold O. Jun. Douglass, Bernard Fisher, J. Michael Hamilton, Michael Friedman, Richard Simon, Harry S. Wieand

Publication date 30 June 1999

Published in Communications in Statistics: Theory and Methods (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1080/03610929808832163

zbMATH Keywords

conditional independenceexponential componentscolorectal adjuvant clinical trials

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Recommendations

• Exploring and validating surrogate endpoints in colorectal cancer
• Statistical evaluation of surrogate endpoints with examples from cancer clinical trials
• Analyzing survival data in conjunction with time-dependent surrogate endpoints in clinical trials
• Validation of Surrogate end Points in Multiple Randomized Clinical Trials with Failure Time end Points
• Comparative assessment of trial-level surrogacy measures for candidate time-to-event surrogate endpoints in clinical trials

Cites work

• A Stochastic Model for Censored-Survival Data in the Presence of an Auxiliary Variable
• A Two-Stage Procedure for Survival Studies with Surrogate Endpoints
• Analyzing survival data in conjunction with time-dependent surrogate endpoints in clinical trials
• Inference using surrogate outcome data and a validation sample
• Using surrogate failure time data to increase cost effectiveness in clinical trials

Cited in

(2)

• Improving efficiency in clinical trials using auxiliary information: Application of a multi‐state cure model
• Exploring and validating surrogate endpoints in colorectal cancer

This page was built for publication: Investigation of disease-free survival as a surrogate endpoint for survival in cancer clinical trials

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q3842893)