Sequential medical trials involving paired data

DOI10.1093/biomet/68.1.119zbMath0466.62073OpenAlexW2058041325MaRDI QIDQ3918943

Herman Chernoff, A. John Petkau

Publication date: 1981

Published in: Biometrika (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1093/biomet/68.1.119

zbMATH Keywords

heat equationWiener processfree boundary problemclinical trialsasymptotic resultsBayes riskpaired datasequential medical trialscontinuous time versionnumerical descriptions

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Bayesian problems; characterization of Bayes procedures (62C10) Stopping times; optimal stopping problems; gambling theory (60G40) Sequential statistical analysis (62L10) Optimal stopping in statistics (62L15)

Related Items (7)

Generalization of a lemma of kiefer and weiss for the case of sequentially planned decision problems with more than two hypotheses ⋮ Truncated sequential medical trials involving paired data ⋮ Herbert Robbins and sequential analysis ⋮ Anscombe’s model for sequential clinical trials revisited ⋮ Optimal stopping for Brownian motion with applications to sequential analysis and option pricing ⋮ Evaluation of asymptotic approximations for a two-stage Bernoulli bandit ⋮ Incorporating scientific, ethical and economic considerations into the design of clinical trials in the pharmaceutical industry: a sequential approach

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