Estimating Michaelis-Menten Parameters: Bias, Variance and Experimental Design

DOI10.2307/2529871MaRDI QIDQ3968360zbMATH OpenOpenAlexFDO

Authors David Currie

Publication date 1982

Published in Biometrics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.2307/2529871

zbMATH Keywords

maximum likelihoodbiasvarianceenzyme kineticsminimum variance unbiased estimatesestimating Michaelis-Menten parameters

Mathematics Subject Classification ID

General nonlinear regression (62J02) Applications of statistics to biology and medical sciences; meta analysis (62P10) Optimal statistical designs (62K05) Design of statistical experiments (62K99)

Cited in

(10)

• Inference for nonconjugate Bayesian Models using the Gibbs sampler
• Optimal two-point designs for the michaelis-menten model with heteroscedastic errors
• Corrected confidence intervals for adaptive nonlinear regression models
• Optimal Designs When the Variance Is A Function of the Mean
• Fitting the Michaelis-Menten model
• Estimation of the Michaelis-Menten parameters for reductive dechlorination of chlorinated solvents
• Two-stage estimation and simultaneous confidence band in partially nonlinear additive model
• The asymptotic properties of the Cornish-Bowden-Eisenthal median estimator
• Robust inference for nonlinear regression models
• Nonlinear regression modelling: a primer with applications and caveats

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