Evolutionary Walks on Rugged Landscapes

DOI10.1137/0151040zbMath0755.92014OpenAlexW2006492954MaRDI QIDQ3978564

Catherine A. Macken, Alan S. Perelson, Patrick S. Hagan

Publication date: 25 June 1992

Published in: SIAM Journal on Applied Mathematics (Search for Journal in Brave)

Full work available at URL: https://semanticscholar.org/paper/ff37111262dcf714d03efb8ca9a2e4d63b2917f0

zbMATH Keywords

amino acidssomatic hypermutationmolecular evolutionfitness landscapeimmune responsenucleic acidslocal optimaantibodyprotein moleculesantigensomatic mutationevolutionary walksrandom point mutations

Mathematics Subject Classification ID

Problems related to evolution (92D15) Combinatorial optimization (90C27)

Related Items (16)

Uniform recursive trees: branching structure and simple random downward walk ⋮ Rugged and Elementary Landscapes ⋮ Universality classes of interaction structures for NK fitness landscapes ⋮ Combinatorial vector fields and the valley structure of fitness landscapes ⋮ A minimum on the mean number of steps taken in adaptive walks ⋮ Quasispecies and recombination ⋮ Properties of adaptive walks on uncorrelated landscapes under strong selection and weak mutation ⋮ Geometry of fitness landscapes: peaks, shapes and universal positive epistasis ⋮ Rigorous results for the NK model. ⋮ Analysis of adaptive walks on NK fitness landscapes with different interaction schemes ⋮ Problem solving by heterogeneous agents ⋮ Global optima results for the Kauffman \(NK\) model ⋮ Dynamics of local search trajectory in traveling salesman problem ⋮ Evolutionary accessibility of modular fitness landscapes ⋮ New global optima results for the Kauffman \(NK\) model: Handling dependency ⋮ Self-organized criticality and partial synchronization in an evolving network

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