A global model to define the behavior of partial agonists (bell-shaped dose-response inducers) in pharmacological evaluation of activity in the presence of the full agonist

DOI10.1080/10543409808835266zbMath0911.62100WikidataQ52229425 ScholiaQ52229425MaRDI QIDQ4221323

Francisco J. López, Krishnendu Ghosh, Emily S. Shen, Brian J. Arey

Publication date: 11 March 1999

Published in: Journal of Biopharmaceutical Statistics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1080/10543409808835266

zbMATH Keywords

dose-response models; nonlinear fitting; bell-shaped curves; four-parameter logistic equation; FSH receptors; FSH-receptors; partial agonist; seven-parameter logistic equation

Mathematics Subject Classification ID

62P10: Applications of statistics to biology and medical sciences; meta analysis

62J02: General nonlinear regression

92C45: Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.)