A current-based model for time interval omission in Markov single ion channel gating mechanisms

DOI10.1080/15326349908807557MaRDI QIDQ4267516zbMATH OpenOpenAlexFDO

Authors Tom Winch, Frank Ball

Publication date 18 July 2000

Published in Communications in Statistics. Stochastic Models (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1080/15326349908807557

zbMATH Keywords

equilibrium behaviourfluid modelreversed processsemi-Markov sequencesingle ion channel modellingtime interval omission

Mathematics Subject Classification ID

Applications of Markov chains and discrete-time Markov processes on general state spaces (social mobility, learning theory, industrial processes, etc.) (60J20) Continuous-time Markov processes on discrete state spaces (60J27) Markov renewal processes, semi-Markov processes (60K15) Cell biology (92C37)

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• A note on single-channel autocorrelation functions
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• Properties of single ion channel currents elicted by a pulse of agonist concentration or voltage
• Empirical clustering of bursts of openings in markov and semi-markov models of single channel gating incorporating time interval omission
• Modelling modal gating of ion channels with hierarchical Markov models
• Marked continuous-time Markov chain modelling of burst behaviour for single ion channels

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