Modeling the Ames Salmonella/Microsome Assay

DOI10.2307/2532562zbMATH Open0794.62072OpenAlexW2332140556WikidataQ50162248 ScholiaQ50162248MaRDI QIDQ4274334FDOQ4274334

Authors: Brian G. Leroux, Susana Bleuer, Louis H. Broekhoven, D. Krewski 

Publication date: 13 January 1994

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.2307/2532562

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zbMATH Keywords

quasi-likelihood methoddiffusion of histidineAmes Salmonella/microsome assaygrowth of auxotrophic bacteriahistidine-independent prototrophic cellsreverse mutationstests for mutagenicity

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cited In (3)

• Model-Based Statistical Procedures for the Analysis of in Vitro Mutagenesis Assays
• Two stage model for carcinogenesis: Number and size distributions of premalignant clones in longitudinal studies
• Quantitative correlation of the \textit{in vitro} biological effect with parameters of molecular complexation in mutagen-interceptor systems

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