Sequential method of estimating the LD50 using a modified up-and-down rule

DOI10.1080/10543409408835069MaRDI QIDQ4298667zbMATH OpenOpenAlexWikidataFDO

Authors

Publication date 18 August 1994

Published in Journal of Biopharmaceutical Statistics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1080/10543409408835069

Mathematics Subject Classification ID

Sequential estimation (62L12) Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites work

• A Method for Obtaining and Analyzing Sensitivity Data
• A method for the solution of certain non-linear problems in least squares
• A Stochastic Approximation Method
• An Algorithm for Least-Squares Estimation of Nonlinear Parameters
• Continual Reassessment Method: A Practical Design for Phase 1 Clinical Trials in Cancer
• Design and Analysis of Phase I Clinical Trials
• Interval Estimation of the LD 50 Based on an Up-and-down Experiment
• Some New Aspects of the Application of Maximum Likelihood to the Calculation of the Dosage Response Curve
• Some Properties of the Spearman Estimator in Bioassay
• The Up-and-Down Method with Small Samples

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