General Formulas for Obtaining the MLEs and the Asymptotic Variance- Covariance Matrix in Mapping Quantitative Trait Loci When Using the EM Algorithm

DOI10.2307/2533965zbMATH Open0878.62083OpenAlexW2118902965WikidataQ44868385 ScholiaQ44868385MaRDI QIDQ4349980FDOQ4349980

Chen-Hung Kao, Zhao-Bang Zeng

Publication date: 27 August 1997

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.2307/2533965

Recommendations

• The Full EM Algorithm for the MLEs of QTL Effects and Positions and Their Estimated Variances in Multiple‐Interval Mapping
• On some statistical aspects of the interval mapping for QTL detection
• Interval Mapping for Quantitative Trait Loci Detection in Finite Mixture Models with General Kernel Functions
• Maximum likelihood estimation of genetic parameters
• Multiple interval mapping for quantitative trait loci via EM algorithm in the presence of crossover interference

zbMATH Keywords

epistasisheritabilityEM algorithmmaximum likelihoodquantitative trait locigene mappingnormal mixture modelasymptotic variance-covariance matrixgeneral formulas

Mathematics Subject Classification ID

Point estimation (62F10) Applications of statistics to biology and medical sciences; meta analysis (62P10) Estimation in multivariate analysis (62H12) Genetics and epigenetics (92D10)

Cited In (8)

• Mixture Generalized Linear Models for Multiple Interval Mapping of Quantitative Trait Loci in Experimental Crosses
• Parametric and semiparametric methods for mapping quantitative trait loci
• The Full EM Algorithm for the MLEs of QTL Effects and Positions and Their Estimated Variances in Multiple‐Interval Mapping
• An explicit representation of the limit of the LRT for interval mapping of quantitative trait loci
• Multiple Interval Mapping for Quantitative Trait Loci via EM Algorithm in the Presence of Crossover Interference
• Interval Mapping of Quantitative Trait Loci for Time‐to‐Event Data with the Proportional Hazards Mixture Cure Model
• Title not available (Why is that?)
• Influence analysis in quantitative trait loci detection

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