Optimal Design for ELISA and Other Forms of Immunoassay

DOI10.2307/1270904MaRDI QIDQ4365697zbMATH OpenOpenAlexFDO

Authors David M. Rocke, G. Jones

Publication date 15 December 1997

Published in Technometrics (Search for Journal in Brave)

Full work available at URL https://escholarship.org/uc/item/81q6c32n

zbMATH Keywords

calibrationprecisionimmunoassayenzyme-linked immunosorbent assaylog-logistic curve

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Optimal statistical designs (62K05)

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• Conceptual and statistical issues in the validation of analytic dilution assays for pharmaceutical applications
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• Modelling random antibody adsorption and immunoassay activity
• Comparisons of titer estimation methods for multiplexed pneumococcal opsonophagocytic Killing assay
• Predicting protein concentrations with ELISA microarray assays, monotonic splines and Monte Carlo simulation

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