Kinetics of active surface-mediated diffusion in spherically symmetric domains
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Publication:438828
DOI10.1007/S10955-012-0496-8zbMATH Open1246.82084arXiv1206.2756OpenAlexW3099511626MaRDI QIDQ438828FDOQ438828
Authors: J.-F. Rupprecht, O. Bénichou, D. S. Grebenkov, Raphael Voituriez
Publication date: 31 July 2012
Published in: Journal of Statistical Physics (Search for Journal in Brave)
Abstract: We present an exact calculation of the mean first-passage time to a target on the surface of a 2D or 3D spherical domain, for a molecule alternating phases of surface diffusion on the domain boundary and phases of bulk diffusion. We generalize the results of [J. Stat. Phys. {�f 142}, 657 (2011)] and consider a biased diffusion in a general annulus with an arbitrary number of regularly spaced targets on a partially reflecting surface. The presented approach is based on an integral equation which can be solved analytically. Numerically validated approximation schemes, which provide more tractable expressions of the mean first-passage time are also proposed. In the framework of this minimal model of surface-mediated reactions, we show analytically that the mean reaction time can be minimized as a function of the desorption rate from the surface.
Full work available at URL: https://arxiv.org/abs/1206.2756
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- Exit time distribution in spherically symmetric two-dimensional domains
- Bulk mediated surface diffusion: non Markovian and biased behavior
- Run-and-tumble particles, telegrapher's equation and absorption problems with partially reflecting boundaries
- Mean exit time for surface-mediated diffusion: spectral analysis and asymptotic behavior
- On the diffusion of circular domains on a spherical vesicle
- An encounter-based approach for restricted diffusion with a gradient drift
- First-passage times of multiple diffusing particles with reversible target-binding kinetics
- Bulk-mediated Surface Diffusion on a Cylinder in the Fast Exchange Limit
- The narrow escape problem in a circular domain with radial piecewise constant diffusivity
- Accumulation times for diffusion-mediated surface reactions
- Conditional mean first passage times to small traps in a 3-D domain with a sticky boundary: applications to T cell searching behavior in lymph nodes
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