Easy-to-implement Bayesian methods for dose-escalation studies in healthy volunteers

DOI10.1093/biostatistics/2.1.47zbMath1017.62120OpenAlexW2123383793WikidataQ47671191 ScholiaQ47671191MaRDI QIDQ4419374

Stephen Francis, John Whitehead, Yinghui Zhou, Scott Patterson, Dawn Webber

Publication date: 13 August 2003

Published in: Biostatistics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1093/biostatistics/2.1.47

zbMATH Keywords

pharmacokineticsphase I trialdose-escalationfirst-into-man

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Bayesian inference (62F15) Bayesian problems; characterization of Bayes procedures (62C10)

Related Items (5)

Dose‐finding methods for Phase I clinical trials using pharmacokinetics in small populations ⋮ Adaptive Bayesian compound designs for dose finding studies ⋮ Adaptive designs for selecting drug combinations based on efficacy-toxicity response ⋮ Implementation of a Bayesian Design in a Dose‐Escalation Study of an Experimental Agent in Healthy Volunteers ⋮ Bayesian Optimal Designs for Phase I Clinical Trials

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