Dynamics of a two-receptor binding model: how affinities and capacities translate into long and short time behaviour and physiological corollaries

DOI10.3934/DCDSB.2012.17.2171MaRDI QIDQ449305zbMATH OpenOpenAlexFDO

Authors Lambertus A. Peletier, Willem De Winter, An Vermeulen

Publication date 12 September 2012

Published in Discrete and Continuous Dynamical Systems. Series B (Search for Journal in Brave)

Full work available at URL https://doi.org/10.3934/dcdsb.2012.17.2171

zbMATH Keywords

protein bindingsingular perturbation theorysystems pharmacologytarget-mediated drug disposition

Mathematics Subject Classification ID

Transformation and reduction of ordinary differential equations and systems, normal forms (34C20) Qualitative investigation and simulation of ordinary differential equation models (34C60) Singular perturbations of ordinary differential equations (34D15) Systems biology, networks (92C42) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

Recommendations

• Dynamics of target-mediated drug disposition: how a drug reaches its target
• Modeling drug-protein dynamics
• Asymptotic analysis of a TMDD model: when a reaction contributes to the destruction of its product
• A mathematical analysis of rebound in a target-mediated drug disposition model. I: Without feedback
• scientific article; zbMATH DE number 1462112

Cited in

(5)

• A mathematical analysis of rebound in a target-mediated drug disposition model. II. With feedback
• A mathematical analysis of rebound in a target-mediated drug disposition model. I: Without feedback
• Asymptotic analysis of a target-mediated drug disposition model: algorithmic and traditional approaches
• Modeling drug-protein dynamics
• Dynamics of target-mediated drug disposition: how a drug reaches its target

This page was built for publication: Dynamics of a two-receptor binding model: how affinities and capacities translate into long and short time behaviour and physiological corollaries

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q449305)