On instrumental variables estimation of causal odds ratios

DOI10.1214/11-STS360zbMATH Open1246.62224arXiv1201.2487OpenAlexW1978032907WikidataQ58819094 ScholiaQ58819094MaRDI QIDQ449850FDOQ449850

Authors: Els Goetghebeur, Stijn Vansteelandt, Jack Bowden, Manoochehr Babanezhad 

Publication date: 1 September 2012

Published in: Statistical Science (Search for Journal in Brave)

Abstract: Inference for causal effects can benefit from the availability of an instrumental variable (IV) which, by definition, is associated with the given exposure, but not with the outcome of interest other than through a causal exposure effect. Estimation methods for instrumental variables are now well established for continuous outcomes, but much less so for dichotomous outcomes. In this article we review IV estimation of so-called conditional causal odds ratios which express the effect of an arbitrary exposure on a dichotomous outcome conditional on the exposure level, instrumental variable and measured covariates. In addition, we propose IV estimators of so-called marginal causal odds ratios which express the effect of an arbitrary exposure on a dichotomous outcome at the population level, and are therefore of greater public health relevance. We explore interconnections between the different estimators and support the results with extensive simulation studies and three applications.

Full work available at URL: https://arxiv.org/abs/1201.2487

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zbMATH Keywords

causal effectmarginal effectlogistic structural mean modelMendelian randomization

Mathematics Subject Classification ID

Estimation in survival analysis and censored data (62N02) Applications of statistics to biology and medical sciences; meta analysis (62P10)

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Cited In (27)

• Structural nested models and G-estimation: the partially realized promise
• Estimating structural mean models with multiple instrumental variables using the generalised method of moments
• The Case‐Only Odds Ratio as a Causal Parameter
• Instrumental variables and inverse probability weighting for causal inference from longitudinal observational studies
• IV estimation without distributional assumptions
• Efficient and flexible estimation of natural direct and indirect effects under intermediate confounding and monotonicity constraints
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• Estimating peer effects in longitudinal dyadic data using instrumental variables
• Odds are the sign is right
• A note on the control function approach with an instrumental variable and a binary outcome
• On the partial identification of a new causal measure for ordinal outcomes
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• Discussion On “Instrumental Variable Estimation of the Causal Hazard Ratio” by Linbo Wang, Eric Tchetgen Tchetgen, Torben Martinussen, and Stijn Vansteelandt
• Estimating and contextualizing the attenuation of odds ratios due to non collapsibility
• Coverage probability of E-estimator for the effect of dichotomous exposure
• Likelihood analysis of the binary instrumental variable model
• Selection and integration of generalized instrumental variables for estimating total effects
• Instrumental variables: an econometrician's perspective
• Estimating a Marginal Causal Odds Ratio Subject to Confounding
• Causal proportional hazards estimation with a binary instrumental variable
• On the estimation accuracy of causal effects using supplementary variables
• The risk of maternal complications after Cesarean delivery: near-far matching for instrumental variables study designs with large observational datasets
• A causal proportional hazards estimator under homogeneous or heterogeneous selection in an IV setting
• On the use of the Lasso for instrumental variables estimation with some invalid instruments
• Formulating causal questions and principled statistical answers
• Instrumental variable estimation with the R package \texttt{ivtools}
• Instrumental variable estimators for binary outcomes

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