OPTIMAL SAMPLING TIMES IN BIOEQUIVALENCE TESTS

DOI10.1081/BIP-100101011zbMATH Open0953.62116WikidataQ73530648 ScholiaQ73530648MaRDI QIDQ4512648FDOQ4512648

Authors: Fan Hui Kong, René Gonin 

Publication date: 29 January 2001

Published in: Journal of Biopharmaceutical Statistics (Search for Journal in Brave)

Recommendations

• Optimal Sampling Times in Population Pharmacokinetic Studies
• Optimal confidence sets for testing average bioequivalence.
• Determining average bioequivalence and corresponding sample sizes in general asymmetric settings
• Statistical considerations in bioequivalence of two area under the concentration-time curves obtained from serial sampling data

zbMATH Keywords

bioequivalencecompartment modelbioavailabilityoptimal sampling designconcentration-time curve

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites Work

• Optimal selection procedures for abbreviated area under the curve (aauc) of blood concentration versus time for drug blood concentration levels

Cited In (6)

• Sample reuse Simulation in Optimal Design for Tmax in Pharmacokinetic Experiments
• Optimal and Robust Designs for Estimating the Concentration Curve and the AUC
• Optimal selection procedures for abbreviated area under the curve (aauc) of blood concentration versus time for drug blood concentration levels
• Experimental designs for the estimation of the concentration curve and the AUC
• Assessing systemic drug exposure in repeated dose toxicity studies in the case of complete and incomplete sampling
• Optimal Sampling Times in Population Pharmacokinetic Studies

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