The role of minimal sets in dose finding studies

DOI10.1080/10485252.2018.1515430zbMath1418.62390OpenAlexW2889121456MaRDI QIDQ4559466

Matthieu Clertant, John O'Quigley

Publication date: 3 December 2018

Published in: Journal of Nonparametric Statistics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1080/10485252.2018.1515430

zbMATH Keywords

hierarchical modelclinical trialcontinual reassessment methodsequential designdose finding methodology

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Nonparametric estimation (62G05) Sequential statistical design (62L05)

Related Items (1)

Semiparametric Dose Finding Methods for Partially Ordered Drug Combinations

Cites Work

• Continual Reassessment Method: A Practical Design for Phase 1 Clinical Trials in Cancer
• The treatment versus experimentation dilemma in dose finding studies
• A stochastic approximation by observations on a discrete lattice using isotonic regression
• Cumulative cohort design for dose-finding
• Design and Analysis of Phase I Clinical Trials
• Continual Reassessment Method: A Likelihood Approach
• Semiparametric Dose Finding Methods
• Non-parametric optimal design in dose finding studies

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