Linear combination test for hierarchical gene set analysis

DOI10.2202/1544-6115.1641MaRDI QIDQ458220zbMATH OpenOpenAlexWikidataFDO

Authors Xiaoming Wang, Irina Dinu, Wei Liu, Yutaka Yasui

Publication date 7 October 2014

Published in Statistical Applications in Genetics and Molecular Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.2202/1544-6115.1641

zbMATH Keywords

gene expressionDNA microarraysgene-set analysis (GSA)

Mathematics Subject Classification ID

General biostatistics (92B15) Genetics and epigenetics (92D10)

Recommendations

• On testing the significance of sets of genes
• Improved statistical tests for differential gene expression by shrinking variance components estimates
• A two-sample test for high-dimensional data with applications to gene-set testing
• Multivariate approach for selecting sets of differentially expressed genes
• Random-set methods identify distinct aspects of the enrichment signal in gene-set analysis

Cited in

(5)

• On testing the significance of sets of genes
• Global adaptive rank truncated product method for gene-set analysis in association studies
• A GS-CORE algorithm for performing a reduction test on multiple gene sets and their core genes
• Rotation gene set testing for longitudinal expression data
• Statistical tests for the intersection of independent lists of genes: sensitivity, FDR, and type I error control

This page was built for publication: Linear combination test for hierarchical gene set analysis

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q458220)